Patients say yes without fully understanding.

Consent captures a signature. It does not create understanding.Protocols define participation. They do not prepare people for it.CORE closes the gap before confusion becomes dropout.

Talk to a Patient Experience Expert

Traditional education creates downstream failure.CORE prevents it upstream.

What today looks like

  • Generic materials misaligned to protocol
  • Consent doubles as first-time education
  • Caregivers excluded
  • Sites absorb re-explanation
  • Amendments reset understanding

What CORE changes

  • Trial-specific, protocol-derived
  • Understanding built before consent
  • Caregiver-inclusive by default
  • Sites receive prepared patients
  • Amendment-resilient updates

Complete study execution coverage via a system that removes gaps.

CORE maps every trial lifecycle stage to specific education, expectation-setting, and decision support that patients need to participate successfully.

1
Awareness & Entry
Trial overviews, referral guides, awareness materials
Risk if missing: Incomplete or distorted understanding at entry
2
Education & Readiness
Full education guides, burden translation, visit schedules
Risk if missing: Expectation mismatch, early dropout
3
Prescreening & Enrollment
Pre-consent education, eligibility explanation, consent support
Risk if missing: Confusion at decision point
4
Participation
Visit prep, "what to expect" guides, adherence support
Risk if missing: Dropout driven by friction
5
Completion & Closeout
Completion guidance, transition expectations, follow-up clarity
Risk if missing: Loss of completion and poor experience

All materials are protocol-derived, behaviorally structured, IRB-ready, consistent across sites, and amendment-resilient. CORE removes execution risk at every stage where confusion, fear, or unmet expectation derails participation.

See the full lifecycle deep dive →

From insight to experience to impact.

CORE follows a structured three-phase process. Each phase answers a specific question. Each phase produces output that feeds the next. Nothing is created from assumption. Nothing is built without clarity on what it must accomplish. Full deployment happens in weeks, not months.

01
Start With Data
Map what blocks understanding, trust, and action for this trial. Protocol friction mapping. Patient and caregiver comprehension gaps. Site education burden. Output: an operational map of what must be explained, to whom, in what sequence, and at what moment in the lifecycle.
02
Design the Experience
Design how understanding should unfold for this patient, in this trial, over time. Decision-point mapping. Sequencing framework. Comprehension milestones. Caregiver integration touchpoints. Output: a structured education architecture independent of format.
03
Produce Assets That Perform
Every asset has a defined role. Nothing is created to fill a deliverable list. Protocol-derived. Behaviorally structured. IRB-ready. Multilingual. Amendment-resilient. Delivered in weeks. Output: a coordinated set of materials that create the experience the design phase specified.

Understanding is Never Assumed

Traditional patient education informs. Clinical trials demand commitment. CORE bridges that gap with behavioral design: decision architecture over information delivery, sequencing over compression, expectation alignment over persuasion, feasibility framing over clinical framing, caregiver integration by default, amendment resilience over static delivery.

Patients don't struggle from lacking information. They struggle translating information into real-life feasibility. CORE sequences how decisions unfold, not how protocols are written. It helps patients answer "Can I really do this?" not just "What is this?"

Protocols change. CORE does not break.

Amendments are the number one reason traditional patient education fails mid-study. Generic, monolithic materials get rebuilt from scratch. Timelines reset. Patient understanding regresses. CORE's modular architecture preserves what works and updates only what changed.

Step 1
Amendment Issued

Protocol change identified. Scope assessed against existing CORE materials.

Step 2
Impact Mapping

Affected lifecycle stages and assets identified. Unaffected materials remain in service.

Step 3
Targeted Update

Only impacted components revised. Patient understanding already built is preserved.

Traditional Approach

  • Materials rebuilt from scratch
  • Timeline resets by weeks or months
  • Sites use outdated content during rebuild
  • Patient understanding regresses
  • Cost doubles each amendment cycle

CORE Approach

  • Only impacted modules updated
  • Turnaround in days, not weeks
  • Unaffected materials remain live
  • Patient understanding is preserved
  • Investment compounds across amendments

Caregivers a readiness variable

In most trials, caregivers determine feasibility. They manage schedules, transportation, medication, support, and decisions. Caregiver readiness and patient readiness are inseparable. A prepared patient with an unprepared caregiver is a retention risk. CORE eliminates the gap by design.

Role Definition

A concrete map of time commitment, decision points, physical presence, and emotional labor. Caregivers know what they are agreeing to before the patient consents.

Burden Translation

Protocol burden falls on caregivers differently. CORE translates requirements into caregiver-specific terms: schedule, work, travel, cognitive load.

Decision Partnership

Caregivers participate in enrollment, continuation, and withdrawal decisions. Decision support is built for the caregiver's perspective.

If it only delivers content, it is not CORE.

CORE Is

  • A trial execution system for patient readiness education
  • Protocol-derived, behaviorally structured, IRB-ready
  • A system covering all 5 lifecycle stages of participation
  • Built for patients, caregivers, sites, and HCPs
  • Designed to start fast, expand deliberately, reuse across trials
  • The foundational experience layer within PRISM

CORE Is Not

  • A creative agency or content shop
  • A generic content library or template collection
  • A one-time deliverable
  • An informational brochure with softer language
  • A recruitment or media solution
  • A replacement for sites, CROs, clinical teams

Purpose-built. Ready to deploy

CORE delivers through modular assets, each grounded in insight, designed for comprehension, built for reuse and scale.

Patient & caregiver websites
Educational & explainer videos
Digital & print brochures
Condition & trial education hubs
HCP & site-facing materials
Multilingual & culturally adapted content

Start with one asset. Prove value quickly with live deployment. Expand across indications, trials, populations. Reuse and adapt without rebuilding.

View the Full CORE Catalog

When execution is controlled,
the downstream numbers change.

Poor execution creates screen failure, early dropout, site burden, delays, and rescue spend. Every confusion point becomes a cost center. CORE prevents structural inefficiency by preparing patients before trials absorb the cost of confusion.

Stabilized enrollment curves through aligned expectations that remove screen-failure spikes and slow ramps
Improved retention from readiness built before consent that translates to commitment after enrollment
Reduced site burnout because sites stop re-explaining what should never have been left ambiguous
Fewer rescue cycles because expectation mismatch gets prevented, not patched

Three levers. One execution system.

01

Stabilizing Trial Economics

By preventing avoidable dropout and rescue, CORE materially reduces cost per completer and protects timeline integrity.

02

Reducing Site Friction

CORE delivers prepared patients to sites by establishing understanding and aligning expectations upfront, reducing rework, escalations, and coordinator burnout.

03

Engineering Completion

CORE turns completion from a hope into a designed outcome by making readiness an explicit, governed input to participation.

Already the patient-readiness partner of choice.

Powering 17 of the world's top 25 pharmaceutical companies.

100+
Clients
300+
Clinical Studies
72,000+
Patients
270+
Conditions

Frequently Asked Questions

What is CORE?

CORE is Jumo Health's trial execution system for patient readiness education. It translates protocol design into structured, behaviorally informed education for patients, caregivers, and sites across five lifecycle stages. Protocol-derived. IRB-ready. Deployed in weeks.

How is CORE different from an agency or content library?

Agencies are creative-led and slow. Content libraries store generic assets. CORE is execution-first, protocol-derived, and behaviorally structured. Every asset has a defined role, mapped to a specific decision point in the trial lifecycle.

How fast can CORE be deployed?

CORE deploys in six to eight weeks. Pre-built behavioral formats and structured outputs eliminate long creative cycles, scope drift, and rework. Standard package first, then expansion by protocol complexity.

Can CORE handle protocol amendments?

Yes. CORE materials are amendment-resilient. Modular assets update only the impacted components without resetting patient understanding. Turnaround in days, not weeks.

How does CORE address caregivers?

Caregivers are a readiness variable, not an audience. CORE includes role definition, burden translation, and decision partnership in every stage. Caregiver readiness and patient readiness are inseparable.

How is CORE different from PRISM?

CORE is a trial execution system for patient readiness education. PRISM is a full operating system: education plus readiness intelligence, governed advancement, and retention monitoring. Deploy CORE standalone or as the foundational layer within PRISM.

Key Definitions

Proprietary constructs defined by Jumo Health. Each one is a measurable operational concept, not a marketing term. View all definitions →

Patient Readiness
The measurable probability that an enrolled participant will complete a trial through its final visit.
Cognitive Friction
The gap between what a protocol requires a patient to understand and what they actually comprehend.
Readiness Friction Map
A diagnostic visualization plotting every barrier a patient population faces across a trial lifecycle.

Send us your protocol and site list.

In two days, you get three execution diagnostics on your program.

01 · The Baseline

Trial Readiness Index

How likely each eligible patient cluster is to activate, persist, and complete, before any intervention.

02 · The Diagnosis

Readiness Friction Map

The barriers most likely to suppress activation, enrollment, and completion in each cluster, and how to mitigate them.

03 · The Prescription

Readiness
Blueprint

Which clusters to target, which barriers to address, which interventions to deploy, and what completion lift to expect.

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